Total launches: 72 (All-weather lifeboat 20 and inshore lifeboat 52)
| Date | Lifeboat | Incident |
| 17/01/10 | ILB | Dory reported adrift off Rosemullion Head |
| 01/02/10 | ILB | Open boat reported adrift off Durgan in the Helford River |
| 02/02/10 | ALB | Irish Ferry Oscar Wilde on Fire 7 miles South of Falmouth |
| 19/02/10 | ILB | Person reported in the water at Pendennis Marina |
| 21/02/10 | ILB | Person reported in the water at Gyllyngvase Beach |
| 07/03/10 | ILB | Capsized sailing dinghy, off Prince of Wales Pier, Falmouth Inner Harbour |
| 02/04/10 | ILB | Yacht Anitra Duck broken down close to Trefusis Point |
| 11/04/10 | ILB | Search for missing person, Penryn & Falmouth shoreline |
| 17/04/10 | ILB | Person requiring medical attention on Yacht Amey, off Mylor Harbour |
| 18/04/10 | ALB & ILB | Search for missing person, between Porthkerris & Coverack |
| 19/04/10 | ILB | Two persons cut off by the tide, between Gyllyngvase & Swanpool |
| 22/04/10 | ALB | Yacht Pogo with fouled propeller, 2 miles South of Dodman Point |
| 23/04/10 | ALB | Concern for person in punt in Falmouth Inner Harbour |
| 27/04/10 | ALB | Yacht Blue Moncha with engine failure and becalmed 1 mile South of Manacles |
| 28/04/10 | ILB | Workboat Westone taking water, Percuil River |
| 04/05/10 | ALB | Yacht Galbrila B becalmed with engine failure, 1.5 miles South East of the Manacles |
| 21/05/10 | ALB & ILB | Report of Fire onboard a Houseboat, Sailors Creek, Penryn River |
| 23/05/10 | ILB | Jet Ski broken down, between Swanpool & Pennance Point |
| 28/05/10 | ILB | Swimmers believed to be in difficulties, off Castle Beach |
| 03/06/10 | ILB | Person in swamped Mirror Dinghy, Carrick Roads |
| 10/06/10 | ILB | Person on yacht requiring medical evacuation, off Durgan, Helford River |
| 12/06/10 | ILB | Five children in an inflatable dinghy being blown offshore, off Carne Beach, Gerrans Bay |
| 12/06/10 | ILB | Report of Capsized Sailing Dinghy, Carrick Roads |
| 03/07/10 | ILB | Swimmer in difficulties, off Gyllyngvase Beach |
| 05/07/10 | ALB & ILB | Fire onboard Pilot Boat Arrow, off Eastern Arms of Falmouth Docks |
| 05/07/10 | ILB | Small tender in difficulties, off Trefusis Point |
| 11/07/10 | ALB | Medical Evacuation from Charter Boat Blue Pointer, 1 mile Northeast of Porthallow |
| 14/07/10 | ALB | Yacht Stravaiger with out power and sails blown out, 37 miles South of Falmouth |
| 17/07/10 | ILB | People reported in the water, Restronguet Creek |
| 18/07/10 | ILB | Open boat broken down, Channals Creek, River Fal |
| 25/07/10 | ALB & ILB | Diver reported overdue, 2.5 miles Southeast of Zone Point |
| 25/07/10 | ILB | Yacht Islander with fouled propeller, off mouth of Helford River |
| 27/07/10 | ILB | Yacht Runcible Moon with fouled propeller, Off Zone Point |
| 30/07/10 | ILB | Open boat broken down, Polwheveral Creek, Helford River |
| 04/08/10 | ILB | Dismasted sailing dinghy, Off Pennance Point |
| 07/08/10 | ILB | Motor Boat L’Diane broken down, Messack Buoy, Carrick Roads |
| 07/08/10 | ILB | Report of unmanned Rigid Inflatable, Off Messack Point, Carrick Roads |
| 07/08/10 | ILB | Small Rigid Inflatable broken down, Off Swanpool Beach |
| 08/08/10 | ILB | Person believed to be in difficulty, Upstream from Boscawen Park, in the Truro River |
| 08/08/10 | ALB & ILB | Yacht Pipeduet II aground, The Hutches, Near Maenporth |
| 15/08/10 | ALB | Overturned Kayak with persons in the water, off Pennance Point |
| 16/08/10 | ILB | Evacuation of injured person from rocks, between Gyllyngvase and Swanpool |
| 17/08/10 | ILB | Capsized Laser 5000 dinghy, off Penarrow Point, Carrick Roads |
| 21/08/10 | ILB | Small Boat broken down, Carrick Roads |
| 21/08/10 | ILB | Capsized sailing dinghy, off Mylor, Carrick Roads |
| 22/08/10 | ILB | Overdue Sunbeam Yacht Clary, Veryan Bay |
| 24/08/10 | ILB | Punt found adrift, Off Loe Beach, Carrick Roads |
| 27/08/10 | ILB | Broken down speed boat, 1 mile Southeast of Pennance Point |
| 28/08/10 | ILB | Diving Medical Emergency, off Gull Rock, Veryan Bay |
| 29/08/10 | ILB | Sailing Boat in adverse weather conditions, off Manacle Buoy |
| 02/09/10 | ILB | Overdue Hire Boat, Helford River |
| 10/09/10 | ILB | Yacht Shady Lady requiring assistance 2 miles Southeast of Zone Point |
| 11/09/10 | ALB | Evacuation of Injured Esaman from Ferry Commodore Goodwill, Falmouth Bay |
| 30/09/10 | ILB | Recovery of Body, Port Pendennis Marina |
| 03/10/10 | ILB | Surfers in difficulty, Porthluney Cove, Veryan Bay |
| 07/10/10 | ILB | Yacht adrift off Gorrangorras Creek, Penryn River |
| 08/10/10 | ALB | Yacht I-Go aground on Lugo Rock |
| 25/10/10 | ILB | Small open boat in difficulties off Penarrow Point, Carrick Roads |
| 28/10/10 | ILB | Safety cover during offloading of casualties from the Container Ship Vega, Carrick Roads |
| 28/10/10 | ALB | Standby and then evacuation of personel from Fish Factory Ship Athena, Falmouth Bay |
| 31/10/10 | ALB | Standby the Sailing Training Vessel Fryderyk Chopin, 20 miles SW of Lizard Point |
| 08/11/10 | ILB | Report of upturned dinghy off Nare Point at entrance to Helford River |
| 12/11/10 | ALB | Yacht Audaciter dismasted 3 miles East South East of Manacle Buoy |
| 26/11/10 | ALB & ILB | Missing stowaway from Mechant Vessel Thuleland, 1.3 miles South of Pendennis Point |
| 10/12/10 | ALB | Sailing Vessel Signe aground on Black Rock at entrance to Falmouth Harbour |
| 10/12/10 | ILB | Report of Windsurfer Board in the water off Nare Head, at entrance Helford River |
